Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function
Identifieur interne : 006142 ( Main/Exploration ); précédent : 006141; suivant : 006143Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function
Auteurs : María Soler Artigas [Royaume-Uni] ; Daan W. Loth [Pays-Bas] ; Louise V. Wain [Royaume-Uni] ; Sina A. Gharib [États-Unis] ; Ma N Obeidat [Royaume-Uni] ; Wenbo Tang [États-Unis] ; Guangju Zhai [Royaume-Uni, Canada] ; Jing Hua Zhao [Royaume-Uni] ; Albert Vernon Smith [Islande] ; Jennifer E. Huffman [Royaume-Uni] ; Eva Albrecht [Allemagne] ; Catherine M. Jackson [Royaume-Uni] ; David M. Evans [Royaume-Uni] ; Gemma Cadby [Canada] ; Myriam Fornage [États-Unis] ; Ani Manichaikul [États-Unis] ; Lorna M. Lopez [Royaume-Uni] ; Toby Johnson [Royaume-Uni] ; Melinda C. Aldrich [États-Unis] ; Thor Aspelund [Islande] ; Inês Barroso [Royaume-Uni] ; Harry Campbell [Royaume-Uni] ; Patricia A. Cassano [États-Unis] ; David J. Couper [États-Unis] ; Gudny Eiriksdottir [Islande] ; Nora Franceschini [États-Unis] ; Melissa Garcia [États-Unis] ; Christian Gieger [Allemagne] ; Gauti Kjartan Gislason [Islande] ; Ivica Grkovic [Croatie] ; Christopher J. Hammond [Royaume-Uni] ; Dana B. Hancock [États-Unis] ; Tamara B. Harris [États-Unis] ; Adaikalavan Ramasamy [Royaume-Uni] ; Susan R. Heckbert [États-Unis] ; Markku Heliövaara [Finlande] ; Georg Homuth [Allemagne] ; Pirro G. Hysi [Royaume-Uni] ; Alan L. James [Australie] ; Stipan Jankovic [Croatie] ; Bonnie R. Joubert [États-Unis] ; Stefan Karrasch [Allemagne] ; Norman Klopp [Allemagne] ; Beate Koch [Allemagne] ; Stephen B. Kritchevsky [États-Unis] ; Lenore J. Launer [États-Unis] ; Yongmei Liu [États-Unis] ; Laura R. Loehr [États-Unis] ; Kurt Lohman [États-Unis] ; Ruth Jf Loos [Royaume-Uni] ; Thomas Lumley [Nouvelle-Zélande] ; Khalid A. Al Balushi [Royaume-Uni] ; Wei Q. Ang [Australie] ; R Graham Barr [États-Unis] ; John Beilby [Australie] ; John D. Blakey [Royaume-Uni] ; Mladen Boban [Croatie] ; Vesna Boraska [Croatie] ; Jonas Brisman [Suède] ; John R. Britton [Royaume-Uni] ; Guy G. Brusselle [Belgique] ; Cyrus Cooper [Royaume-Uni] ; Ivan Curjuric [Suisse] ; Santosh Dahgam [Suède] ; Ian J. Deary [Royaume-Uni] ; Shah Ebrahim [Royaume-Uni, Inde] ; Mark Eijgelsheim [Pays-Bas] ; Clyde Francks [Pays-Bas] ; Darya Gaysina [Royaume-Uni] ; Raquel Granell [Royaume-Uni] ; Xiangjun Gu [États-Unis] ; John L. Hankinson [États-Unis] ; Rebecca Hardy [Royaume-Uni] ; Sarah E. Harris [Royaume-Uni] ; John Henderson [Royaume-Uni] ; Amanda Henry [Royaume-Uni] ; Aroon D. Hingorani [Royaume-Uni] ; Albert Hofman [Pays-Bas] ; Patrick G. Holt [Australie] ; Jennie Hui [Australie] ; Michael L. Hunter [Australie] ; Medea Imboden [Suisse] ; Karen A. Jameson [Royaume-Uni] ; Shona M. Kerr [Royaume-Uni] ; Ivana Kolcic [Croatie] ; Florian Kronenberg [Autriche] ; Jason Z. Liu [Royaume-Uni] ; Jonathan Marchini [Royaume-Uni] ; Tricia Mckeever [Royaume-Uni] ; Andrew D. Morris [Royaume-Uni] ; Anna-Carin Olin [Suède] ; David J. Porteous [Royaume-Uni] ; Dirkje S. Postma [Pays-Bas] ; Stephen S. Rich [États-Unis] ; Susan M. Ring [Royaume-Uni] ; Fernando Rivadeneira [Pays-Bas] ; Thierry Rochat [Suisse] ; Avan Aihie Sayer [Royaume-Uni] ; Ian Sayers [Royaume-Uni] ; Peter D. Sly [Australie] ; George Davey Smith [Royaume-Uni] ; Akshay Sood [États-Unis] ; John M. Starr [Royaume-Uni] ; André G. Uitterlinden [Pays-Bas] ; Judith M. Vonk [Pays-Bas] ; S Goya Wannamethee [Royaume-Uni] ; Peter H. Whincup [Royaume-Uni] ; Cisca Wijmenga [Pays-Bas] ; O Dale Williams [États-Unis] ; Andrew Wong [Royaume-Uni] ; Massimo Mangino [Royaume-Uni] ; Kristin D. Marciante [États-Unis] ; Wendy L. Mcardle [Royaume-Uni] ; Bernd Meibohm [États-Unis] ; Alanna C. Morrison [États-Unis] ; Kari E. North [États-Unis] ; Ernst Omenaas [Norvège] ; Lyle J. Palmer [Canada] ; Kirsi H. Pietil Inen [Finlande] ; Isabelle Pin [France] ; Ozren Polašek [Croatie] ; Anneli Pouta [Finlande] ; Bruce M. Psaty [États-Unis] ; Anna-Liisa Hartikainen [Finlande] ; Taina Rantanen [Finlande] ; Samuli Ripatti [Finlande] ; Jerome I. Rotter [États-Unis] ; Igor Rudan [Royaume-Uni, Croatie] ; Alicja R. Rudnicka [Royaume-Uni] ; Holger Schulz [Allemagne] ; So-Youn Shin [Royaume-Uni] ; Tim D. Spector [Royaume-Uni] ; Ida Surakka [Finlande] ; Veronique Vitart [Royaume-Uni] ; Henry Völzke [Allemagne] ; Nicholas J. Wareham [Royaume-Uni] ; Nicole M. Warrington [Australie, Canada] ; H-Erich Wichmann [Allemagne] ; Sarah H. Wild [Royaume-Uni] ; Jemma B. Wilk [États-Unis] ; Matthias Wjst [Allemagne] ; Alan F. Wright [Royaume-Uni] ; Lina Zgaga [Croatie, Royaume-Uni] ; Tatijana Zemunik [Croatie] ; Craig E. Pennell [Australie] ; Fredrik Nyberg [Suède] ; Diana Kuh [Royaume-Uni] ; John W. Holloway [Royaume-Uni] ; H Marike Boezen [Pays-Bas] ; Debbie A. Lawlor [Royaume-Uni] ; Richard W. Morris [Royaume-Uni] ; Nicole Probst-Hensch [Suisse] ; Jaakko Kaprio [Finlande] ; James F. Wilson [Royaume-Uni] ; Caroline Hayward [Royaume-Uni] ; Mika K Hönen [Finlande] ; Joachim Heinrich [Allemagne] ; Arthur W. Musk [Australie] ; Deborah L. Jarvis [Royaume-Uni] ; Sven Gl Ser [Allemagne] ; Marjo-Riitta J Rvelin [Royaume-Uni, Finlande] ; Bruno H Ch Stricker [Pays-Bas] ; Paul Elliott [Royaume-Uni] ; George T. O Onnor [États-Unis] ; David P. Strachan [Royaume-Uni] ; Stephanie J. London [États-Unis] ; Ian P. Hall [Royaume-Uni] ; Vilmundur Gudnason [Islande] ; Martin D. Tobin [Royaume-Uni]Source :
- Nature genetics [ 1061-4036 ] ; 2011.
Abstract
Pulmonary function measures reflect respiratory health and predict mortality, and are used in the diagnosis of chronic obstructive pulmonary disease (COPD). We tested genome-wide association with the forced expiratory volume in 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) in 48,201 individuals of European ancestry, with follow-up of top associations in up to an additional 46,411 individuals. We identified new regions showing association (combined
Url:
DOI: 10.1038/ng.941
PubMed: 21946350
PubMed Central: 3267376
Affiliations:
- Allemagne, Australie, Autriche, Belgique, Canada, Croatie, Finlande, France, Inde, Islande, Norvège, Nouvelle-Zélande, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Auvergne-Rhône-Alpes, Bavière, Californie, Caroline du Nord, District de Haute-Bavière, Finlande-Centrale, Grand Londres, Groningue (province), Gueldre, Géorgie (États-Unis), Hollande-Méridionale, Maryland, Massachusetts, Midlands de l'Ouest, Nottinghamshire, Nouveau-Mexique, Oxfordshire, Rhône-Alpes, Tennessee, Texas, Uusimaa, Virginie, Washington (État), Écosse, État de New York
- Birmingham, Grenoble, Groningue, Helsinki, Jyväskylä, Londres, Munich, Nimègue, Nottingham, Oxford, Rotterdam, Seattle, Édimbourg
- University College de Londres, Université Joseph Fourier, Université Louis-et-Maximilien de Munich, Université d'Helsinki, Université d'Oxford, Université d'Édimbourg, Université de Jyväskylä, Université de Londres, Université de Nottingham, Université de Washington
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Le document en format XML
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Evans</name><affiliation wicri:level="1"><nlm:aff id="A17">MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Cadby, Gemma" sort="Cadby, Gemma" uniqKey="Cadby G" first="Gemma" last="Cadby">Gemma Cadby</name><affiliation wicri:level="1"><nlm:aff id="A18">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><affiliation wicri:level="2"><nlm:aff id="A20">Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A21">Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Manichaikul, Ani" sort="Manichaikul, Ani" uniqKey="Manichaikul A" first="Ani" last="Manichaikul">Ani Manichaikul</name><affiliation wicri:level="2"><nlm:aff id="A22">Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A23">Department of Public Health Sciences, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, Virginia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, Virginia</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A25">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name><affiliation wicri:level="4"><nlm:aff id="A26">Clinical Pharmacology and the Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and the Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. Aldrich</name><affiliation wicri:level="2"><nlm:aff id="A27">Department of Thoracic Surgery, Vanderbilt University, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Thoracic Surgery, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A28">Division of Epidemiology, Vanderbilt University, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation wicri:level="1"><nlm:aff id="A29">Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A30">University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Cassano, Patricia A" sort="Cassano, Patricia A" uniqKey="Cassano P" first="Patricia A" last="Cassano">Patricia A. Cassano</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Nutritional Sciences, Cornell University Ithaca, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nutritional Sciences, Cornell University Ithaca, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Couper, David J" sort="Couper, David J" uniqKey="Couper D" first="David J" last="Couper">David J. Couper</name><affiliation wicri:level="2"><nlm:aff id="A32">Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Franceschini, Nora" sort="Franceschini, Nora" uniqKey="Franceschini N" first="Nora" last="Franceschini">Nora Franceschini</name><affiliation wicri:level="2"><nlm:aff id="A33">Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Garcia, Melissa" sort="Garcia, Melissa" uniqKey="Garcia M" first="Melissa" last="Garcia">Melissa Garcia</name><affiliation wicri:level="2"><nlm:aff id="A34">Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A15">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gislason, Gauti Kjartan" sort="Gislason, Gauti Kjartan" uniqKey="Gislason G" first="Gauti Kjartan" last="Gislason">Gauti Kjartan Gislason</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Grkovic, Ivica" sort="Grkovic, Ivica" uniqKey="Grkovic I" first="Ivica" last="Grkovic">Ivica Grkovic</name><affiliation wicri:level="1"><nlm:aff id="A35">Croatian Centre for Global Health, The University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, The University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Hammond, Christopher J" sort="Hammond, Christopher J" uniqKey="Hammond C" first="Christopher J" last="Hammond">Christopher J. Hammond</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hancock, Dana B" sort="Hancock, Dana B" uniqKey="Hancock D" first="Dana B" last="Hancock">Dana B. Hancock</name><affiliation wicri:level="2"><nlm:aff id="A36">Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A37">Behavioral Health Epidemiology Program, Research Triangle Institute International, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Behavioral Health Epidemiology Program, Research Triangle Institute International, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="2"><nlm:aff id="A34">Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><affiliation wicri:level="3"><nlm:aff id="A38"> Respiratory Epidemiology and Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Respiratory Epidemiology and Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A39">Department of Epidemiology and Biostatistics, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A40">Department of Medical and Molecular Genetics, King’s College London, Guy’s Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical and Molecular Genetics, King’s College London, Guy’s Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Heckbert, Susan R" sort="Heckbert, Susan R" uniqKey="Heckbert S" first="Susan R" last="Heckbert">Susan R. Heckbert</name><affiliation wicri:level="4"><nlm:aff id="A41">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A43">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><affiliation wicri:level="1"><nlm:aff id="A44">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation wicri:level="1"><nlm:aff id="A45">Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="James, Alan L" sort="James, Alan L" uniqKey="James A" first="Alan L" last="James">Alan L. James</name><affiliation wicri:level="1"><nlm:aff id="A46">Department of Pulmonary Physiology and Sleep Medicine/West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pulmonary Physiology and Sleep Medicine/West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A47">The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Jankovic, Stipan" sort="Jankovic, Stipan" uniqKey="Jankovic S" first="Stipan" last="Jankovic">Stipan Jankovic</name><affiliation wicri:level="1"><nlm:aff id="A35">Croatian Centre for Global Health, The University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, The University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Joubert, Bonnie R" sort="Joubert, Bonnie R" uniqKey="Joubert B" first="Bonnie R" last="Joubert">Bonnie R. Joubert</name><affiliation wicri:level="2"><nlm:aff id="A36">Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Karrasch, Stefan" sort="Karrasch, Stefan" uniqKey="Karrasch S" first="Stefan" last="Karrasch">Stefan Karrasch</name><affiliation wicri:level="4"><nlm:aff id="A49">Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name><affiliation wicri:level="1"><nlm:aff id="A50">Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Koch, Beate" sort="Koch, Beate" uniqKey="Koch B" first="Beate" last="Koch">Beate Koch</name><affiliation wicri:level="1"><nlm:aff id="A51">Department of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine B, University Hospital Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Kritchevsky, Stephen B" sort="Kritchevsky, Stephen B" uniqKey="Kritchevsky S" first="Stephen B" last="Kritchevsky">Stephen B. Kritchevsky</name><affiliation wicri:level="2"><nlm:aff id="A52">Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="2"><nlm:aff id="A34">Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation wicri:level="2"><nlm:aff id="A53">Epidemiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Loehr, Laura R" sort="Loehr, Laura R" uniqKey="Loehr L" first="Laura R" last="Loehr">Laura R. Loehr</name><affiliation wicri:level="2"><nlm:aff id="A33">Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Lohman, Kurt" sort="Lohman, Kurt" uniqKey="Lohman K" first="Kurt" last="Lohman">Kurt Lohman</name><affiliation wicri:level="2"><nlm:aff id="A54">Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Loos, Ruth Jf" sort="Loos, Ruth Jf" uniqKey="Loos R" first="Ruth Jf" last="Loos">Ruth Jf Loos</name><affiliation wicri:level="1"><nlm:aff id="A11">Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Lumley, Thomas" sort="Lumley, Thomas" uniqKey="Lumley T" first="Thomas" last="Lumley">Thomas Lumley</name><affiliation wicri:level="1"><nlm:aff id="A55">Department of Statistics, University of Auckland, Auckland, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Department of Statistics, University of Auckland, Auckland</wicri:regionArea><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Al Balushi, Khalid A" sort="Al Balushi, Khalid A" uniqKey="Al Balushi K" first="Khalid A" last="Al Balushi">Khalid A. Al Balushi</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ang, Wei Q" sort="Ang, Wei Q" uniqKey="Ang W" first="Wei Q" last="Ang">Wei Q. Ang</name><affiliation wicri:level="1"><nlm:aff id="A56">School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Barr, R Graham" sort="Barr, R Graham" uniqKey="Barr R" first="R Graham" last="Barr">R Graham Barr</name><affiliation wicri:level="2"><nlm:aff id="A57">Department of Medicine, Columbia University Medical Center, New York, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Columbia University Medical Center, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation wicri:level="1"><nlm:aff id="A58">Department of Surgery and Pathology, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Surgery and Pathology, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Blakey, John D" sort="Blakey, John D" uniqKey="Blakey J" first="John D" last="Blakey">John D. Blakey</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Boraska, Vesna" sort="Boraska, Vesna" uniqKey="Boraska V" first="Vesna" last="Boraska">Vesna Boraska</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Brisman, Jonas" sort="Brisman, Jonas" uniqKey="Brisman J" first="Jonas" last="Brisman">Jonas Brisman</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Britton, John R" sort="Britton, John R" uniqKey="Britton J" first="John R" last="Britton">John R. Britton</name><affiliation wicri:level="4"><nlm:aff id="A62">Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Brusselle, Guy G" sort="Brusselle, Guy G" uniqKey="Brusselle G" first="Guy G" last="Brusselle">Guy G. Brusselle</name><affiliation wicri:level="1"><nlm:aff id="A63">Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Respiratory Medicine, Ghent University Hospital, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name><affiliation wicri:level="1"><nlm:aff id="A64">MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Curjuric, Ivan" sort="Curjuric, Ivan" uniqKey="Curjuric I" first="Ivan" last="Curjuric">Ivan Curjuric</name><affiliation wicri:level="1"><nlm:aff id="A65">Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">University of Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Basel</wicri:regionArea></affiliation></author><author><name sortKey="Dahgam, Santosh" sort="Dahgam, Santosh" uniqKey="Dahgam S" first="Santosh" last="Dahgam">Santosh Dahgam</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A25">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Ebrahim, Shah" sort="Ebrahim, Shah" uniqKey="Ebrahim S" first="Shah" last="Ebrahim">Shah Ebrahim</name><affiliation wicri:level="3"><nlm:aff id="A67">Non-Communicable Diseases Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Non-Communicable Diseases Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A68">South Asia Centre for Chronic Disease, New Delhi, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>South Asia Centre for Chronic Disease, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Eijgelsheim, Mark" sort="Eijgelsheim, Mark" uniqKey="Eijgelsheim M" first="Mark" last="Eijgelsheim">Mark Eijgelsheim</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Francks, Clyde" sort="Francks, Clyde" uniqKey="Francks C" first="Clyde" last="Francks">Clyde Francks</name><affiliation wicri:level="3"><nlm:aff id="A69">Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Max Planck Institute for Psycholinguistics, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Gaysina, Darya" sort="Gaysina, Darya" uniqKey="Gaysina D" first="Darya" last="Gaysina">Darya Gaysina</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Granell, Raquel" sort="Granell, Raquel" uniqKey="Granell R" first="Raquel" last="Granell">Raquel Granell</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Gu, Xiangjun" sort="Gu, Xiangjun" uniqKey="Gu X" first="Xiangjun" last="Gu">Xiangjun Gu</name><affiliation wicri:level="2"><nlm:aff id="A20">Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Hankinson, John L" sort="Hankinson, John L" uniqKey="Hankinson J" first="John L" last="Hankinson">John L. Hankinson</name><affiliation wicri:level="2"><nlm:aff id="A72">Hankinson Consulting, Inc, Athens, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hankinson Consulting, Inc, Athens, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Hardy, Rebecca" sort="Hardy, Rebecca" uniqKey="Hardy R" first="Rebecca" last="Hardy">Rebecca Hardy</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Harris, Sarah E" sort="Harris, Sarah E" uniqKey="Harris S" first="Sarah E" last="Harris">Sarah E. Harris</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A73">Medical Genetics Section, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Section, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Henderson, John" sort="Henderson, John" uniqKey="Henderson J" first="John" last="Henderson">John Henderson</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Henry, Amanda" sort="Henry, Amanda" uniqKey="Henry A" first="Amanda" last="Henry">Amanda Henry</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hingorani, Aroon D" sort="Hingorani, Aroon D" uniqKey="Hingorani A" first="Aroon D" last="Hingorani">Aroon D. Hingorani</name><affiliation wicri:level="4"><nlm:aff id="A74">Department of Epidemiology and Public Health, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation></author><author><name sortKey="Holt, Patrick G" sort="Holt, Patrick G" uniqKey="Holt P" first="Patrick G" last="Holt">Patrick G. Holt</name><affiliation wicri:level="1"><nlm:aff id="A76">Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A77">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A78">School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Hunter, Michael L" sort="Hunter, Michael L" uniqKey="Hunter M" first="Michael L" last="Hunter">Michael L. Hunter</name><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A78">School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Imboden, Medea" sort="Imboden, Medea" uniqKey="Imboden M" first="Medea" last="Imboden">Medea Imboden</name><affiliation wicri:level="1"><nlm:aff id="A65">Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">University of Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Basel</wicri:regionArea></affiliation></author><author><name sortKey="Jameson, Karen A" sort="Jameson, Karen A" uniqKey="Jameson K" first="Karen A" last="Jameson">Karen A. Jameson</name><affiliation wicri:level="1"><nlm:aff id="A64">MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Kerr, Shona M" sort="Kerr, Shona M" uniqKey="Kerr S" first="Shona M" last="Kerr">Shona M. Kerr</name><affiliation wicri:level="4"><nlm:aff id="A79">Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Kronenberg, Florian" sort="Kronenberg, Florian" uniqKey="Kronenberg F" first="Florian" last="Kronenberg">Florian Kronenberg</name><affiliation wicri:level="1"><nlm:aff id="A80">Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Jason Z" sort="Liu, Jason Z" uniqKey="Liu J" first="Jason Z" last="Liu">Jason Z. Liu</name><affiliation wicri:level="4"><nlm:aff id="A81">Department of Statistics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Statistics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Marchini, Jonathan" sort="Marchini, Jonathan" uniqKey="Marchini J" first="Jonathan" last="Marchini">Jonathan Marchini</name><affiliation wicri:level="4"><nlm:aff id="A81">Department of Statistics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Statistics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Mckeever, Tricia" sort="Mckeever, Tricia" uniqKey="Mckeever T" first="Tricia" last="Mckeever">Tricia Mckeever</name><affiliation wicri:level="4"><nlm:aff id="A62">Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><affiliation wicri:level="1"><nlm:aff id="A82">Medical Research Institute, The University of Dundee, Dundee, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Institute, The University of Dundee, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Olin, Anna Carin" sort="Olin, Anna Carin" uniqKey="Olin A" first="Anna-Carin" last="Olin">Anna-Carin Olin</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Porteous, David J" sort="Porteous, David J" uniqKey="Porteous D" first="David J" last="Porteous">David J. Porteous</name><affiliation wicri:level="4"><nlm:aff id="A79">Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S" last="Postma">Dirkje S. Postma</name><affiliation wicri:level="3"><nlm:aff id="A83">Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Rich, Stephen S" sort="Rich, Stephen S" uniqKey="Rich S" first="Stephen S" last="Rich">Stephen S. Rich</name><affiliation wicri:level="2"><nlm:aff id="A22">Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Ring, Susan M" sort="Ring, Susan M" uniqKey="Ring S" first="Susan M" last="Ring">Susan M. Ring</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation></author><author><name sortKey="Rochat, Thierry" sort="Rochat, Thierry" uniqKey="Rochat T" first="Thierry" last="Rochat">Thierry Rochat</name><affiliation wicri:level="1"><nlm:aff id="A85">Division of Pulmonary Medicine, University Hospitals of Geneva, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Division of Pulmonary Medicine, University Hospitals of Geneva, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Sayer, Avan Aihie" sort="Sayer, Avan Aihie" uniqKey="Sayer A" first="Avan Aihie" last="Sayer">Avan Aihie Sayer</name><affiliation wicri:level="1"><nlm:aff id="A64">MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Sayers, Ian" sort="Sayers, Ian" uniqKey="Sayers I" first="Ian" last="Sayers">Ian Sayers</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sly, Peter D" sort="Sly, Peter D" uniqKey="Sly P" first="Peter D" last="Sly">Peter D. Sly</name><affiliation wicri:level="1"><nlm:aff id="A76">Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name><affiliation wicri:level="1"><nlm:aff id="A17">MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Sood, Akshay" sort="Sood, Akshay" uniqKey="Sood A" first="Akshay" last="Sood">Akshay Sood</name><affiliation wicri:level="2"><nlm:aff id="A86">Department of Medicine, University of New Mexico, Albuquerque, New Mexico, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of New Mexico, Albuquerque, New Mexico</wicri:regionArea><placeName><region type="state">Nouveau-Mexique</region></placeName></affiliation></author><author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A87">Geriatric Medicine Unit, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Geriatric Medicine Unit, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation></author><author><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M" last="Vonk">Judith M. Vonk</name><affiliation wicri:level="3"><nlm:aff id="A88">Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Wannamethee, S Goya" sort="Wannamethee, S Goya" uniqKey="Wannamethee S" first="S Goya" last="Wannamethee">S Goya Wannamethee</name><affiliation wicri:level="4"><nlm:aff id="A89">Department of Primary Care and Population Health, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Primary Care and Population Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Whincup, Peter H" sort="Whincup, Peter H" uniqKey="Whincup P" first="Peter H" last="Whincup">Peter H. Whincup</name><affiliation wicri:level="4"><nlm:aff id="A90">Division of Population Health Sciences and Education, St George’s University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health Sciences and Education, St George’s University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Wijmenga, Cisca" sort="Wijmenga, Cisca" uniqKey="Wijmenga C" first="Cisca" last="Wijmenga">Cisca Wijmenga</name><affiliation wicri:level="3"><nlm:aff id="A91">Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Williams, O Dale" sort="Williams, O Dale" uniqKey="Williams O" first="O Dale" last="Williams">O Dale Williams</name><affiliation wicri:level="3"><nlm:aff id="A92">Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Marciante, Kristin D" sort="Marciante, Kristin D" uniqKey="Marciante K" first="Kristin D" last="Marciante">Kristin D. Marciante</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A41">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Meibohm, Bernd" sort="Meibohm, Bernd" uniqKey="Meibohm B" first="Bernd" last="Meibohm">Bernd Meibohm</name><affiliation wicri:level="2"><nlm:aff id="A93">College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><affiliation wicri:level="2"><nlm:aff id="A21">Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><affiliation wicri:level="2"><nlm:aff id="A33">Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Omenaas, Ernst" sort="Omenaas, Ernst" uniqKey="Omenaas E" first="Ernst" last="Omenaas">Ernst Omenaas</name><affiliation wicri:level="1"><nlm:aff id="A94">Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Centre for Clinical Research, Haukeland University Hospital, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><affiliation wicri:level="1"><nlm:aff id="A18">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H" last="Pietil Inen">Kirsi H. Pietil Inen</name><affiliation wicri:level="1"><nlm:aff id="A95">Obesity Research Unit, Department of Medicine, Division of Internal Medicine, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Obesity Research Unit, Department of Medicine, Division of Internal Medicine, Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A96">Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Pin, Isabelle" sort="Pin, Isabelle" uniqKey="Pin I" first="Isabelle" last="Pin">Isabelle Pin</name><affiliation wicri:level="3"><nlm:aff id="A98">Pédiatrie, Centre Hospitalier Universitaire (CHU), Grenoble, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Pédiatrie, Centre Hospitalier Universitaire (CHU), Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A99">Inserm U823, Centre de Recherche Albert Bonniot, Grenoble, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm U823, Centre de Recherche Albert Bonniot, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A100">Université Joseph Fourier, Grenoble, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Joseph Fourier, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Joseph Fourier</orgName></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A101">Gen-Info Ltd, Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Gen-Info Ltd, Zagreb</wicri:regionArea><wicri:noRegion>Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><affiliation wicri:level="1"><nlm:aff id="A102">Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A41">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A43">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Hartikainen, Anna Liisa" sort="Hartikainen, Anna Liisa" uniqKey="Hartikainen A" first="Anna-Liisa" last="Hartikainen">Anna-Liisa Hartikainen</name><affiliation wicri:level="1"><nlm:aff id="A103">Institute of Clinical Medicine, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Clinical Medicine, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Rantanen, Taina" sort="Rantanen, Taina" uniqKey="Rantanen T" first="Taina" last="Rantanen">Taina Rantanen</name><affiliation wicri:level="4"><nlm:aff id="A104"> Gerontology Research Centre, Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea> Gerontology Research Centre, Department of Health Sciences, University of Jyväskylä, Jyväskylä</wicri:regionArea><orgName type="university">Université de Jyväskylä</orgName><placeName><settlement type="city">Jyväskylä</settlement><region type="région" nuts="2">Finlande-Centrale</region></placeName></affiliation></author><author><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A105">Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="2"><nlm:aff id="A106">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A35">Croatian Centre for Global Health, The University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, The University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A101">Gen-Info Ltd, Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Gen-Info Ltd, Zagreb</wicri:regionArea><wicri:noRegion>Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Rudnicka, Alicja R" sort="Rudnicka, Alicja R" uniqKey="Rudnicka A" first="Alicja R" last="Rudnicka">Alicja R. Rudnicka</name><affiliation wicri:level="4"><nlm:aff id="A90">Division of Population Health Sciences and Education, St George’s University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health Sciences and Education, St George’s University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Schulz, Holger" sort="Schulz, Holger" uniqKey="Schulz H" first="Holger" last="Schulz">Holger Schulz</name><affiliation wicri:level="1"><nlm:aff id="A107">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><affiliation wicri:level="1"><nlm:aff id="A29">Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Surakka, Ida" sort="Surakka, Ida" uniqKey="Surakka I" first="Ida" last="Surakka">Ida Surakka</name><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A105">Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:aff id="A108">Institute for Community Medicine, Study of Health In Pomerania (SHIP)/Clinical Epidemiological Research, University of Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, Study of Health In Pomerania (SHIP)/Clinical Epidemiological Research, University of Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A11">Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Warrington, Nicole M" sort="Warrington, Nicole M" uniqKey="Warrington N" first="Nicole M" last="Warrington">Nicole M. Warrington</name><affiliation wicri:level="1"><nlm:aff id="A56">School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation wicri:level="1"><nlm:aff id="A107">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A109">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A110">Klinikum Grosshadern, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinikum Grosshadern, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Wilk, Jemma B" sort="Wilk, Jemma B" uniqKey="Wilk J" first="Jemma B" last="Wilk">Jemma B. Wilk</name><affiliation wicri:level="2"><nlm:aff id="A111">Division of Aging, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Aging, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Wjst, Matthias" sort="Wjst, Matthias" uniqKey="Wjst M" first="Matthias" last="Wjst">Matthias Wjst</name><affiliation wicri:level="1"><nlm:aff id="A112">Institute of Lung Biology and Disease, Comprehensive Pneumology Center, Helmholtz Zentrum München, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Lung Biology and Disease, Comprehensive Pneumology Center, Helmholtz Zentrum München, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A113">Institute for Medical Statistics and Epidemiology (IMSE), Technical University Munich, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Statistics and Epidemiology (IMSE), Technical University Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Zgaga, Lina" sort="Zgaga, Lina" uniqKey="Zgaga L" first="Lina" last="Zgaga">Lina Zgaga</name><affiliation wicri:level="1"><nlm:aff id="A114">Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb</wicri:regionArea><wicri:noRegion>Zagreb</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E" last="Pennell">Craig E. Pennell</name><affiliation wicri:level="1"><nlm:aff id="A56">School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Nyberg, Fredrik" sort="Nyberg, Fredrik" uniqKey="Nyberg F" first="Fredrik" last="Nyberg">Fredrik Nyberg</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A115">AstraZeneca Research and Development, Mölndal, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>AstraZeneca Research and Development, Mölndal</wicri:regionArea><wicri:noRegion>Mölndal</wicri:noRegion></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Holloway, John W" sort="Holloway, John W" uniqKey="Holloway J" first="John W" last="Holloway">John W. Holloway</name><affiliation wicri:level="1"><nlm:aff id="A116">Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Human Development and Health, Faculty of Medicine, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A117">Infection, Inflammation and Immunity, Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Infection, Inflammation and Immunity, Faculty of Medicine, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Boezen, H Marike" sort="Boezen, H Marike" uniqKey="Boezen H" first="H Marike" last="Boezen">H Marike Boezen</name><affiliation wicri:level="3"><nlm:aff id="A88">Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Lawlor, Debbie A" sort="Lawlor, Debbie A" uniqKey="Lawlor D" first="Debbie A" last="Lawlor">Debbie A. Lawlor</name><affiliation wicri:level="1"><nlm:aff id="A17">MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Richard W" sort="Morris, Richard W" uniqKey="Morris R" first="Richard W" last="Morris">Richard W. Morris</name><affiliation wicri:level="4"><nlm:aff id="A89">Department of Primary Care and Population Health, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Primary Care and Population Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Probst Hensch, Nicole" sort="Probst Hensch, Nicole" uniqKey="Probst Hensch N" first="Nicole" last="Probst-Hensch">Nicole Probst-Hensch</name><affiliation wicri:level="1"><nlm:aff id="A65">Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">University of Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Basel</wicri:regionArea></affiliation></author><author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name><affiliation wicri:level="1"><nlm:aff id="A44">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A96">Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:aff id="A118">Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Heinrich, Joachim" sort="Heinrich, Joachim" uniqKey="Heinrich J" first="Joachim" last="Heinrich">Joachim Heinrich</name><affiliation wicri:level="1"><nlm:aff id="A107">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Musk, Arthur W" sort="Musk, Arthur W" uniqKey="Musk A" first="Arthur W" last="Musk">Arthur W. Musk</name><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A119">Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A78">School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A47">The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Jarvis, Deborah L" sort="Jarvis, Deborah L" uniqKey="Jarvis D" first="Deborah L" last="Jarvis">Deborah L. Jarvis</name><affiliation wicri:level="3"><nlm:aff id="A38"> Respiratory Epidemiology and Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Respiratory Epidemiology and Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A120">MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Gl Ser, Sven" sort="Gl Ser, Sven" uniqKey="Gl Ser S" first="Sven" last="Gl Ser">Sven Gl Ser</name><affiliation wicri:level="1"><nlm:aff id="A121">University Hospital Greifswald, Department of Internal Medicine B, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Greifswald, Department of Internal Medicine B, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><affiliation wicri:level="3"><nlm:aff id="A39">Department of Epidemiology and Biostatistics, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A122">Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A123">Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A102">Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A120">MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A4">Inspectorate of Healthcare, The Hague, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Inspectorate of Healthcare, The Hague</wicri:regionArea><wicri:noRegion>The Hague</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation><affiliation wicri:level="3"><nlm:aff id="A124">Department of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Informatics, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><affiliation wicri:level="3"><nlm:aff id="A120">MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A39">Department of Epidemiology and Biostatistics, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="O Onnor, George T" sort="O Onnor, George T" uniqKey="O Onnor G" first="George T" last="O Onnor">George T. O Onnor</name><affiliation wicri:level="2"><nlm:aff id="A125">Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A126">The National Heart, Lung and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The National Heart, Lung and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><affiliation wicri:level="4"><nlm:aff id="A90">Division of Population Health Sciences and Education, St George’s University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health Sciences and Education, St George’s University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="London, Stephanie J" sort="London, Stephanie J" uniqKey="London S" first="Stephanie J" last="London">Stephanie J. London</name><affiliation wicri:level="2"><nlm:aff id="A36">Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Hall, Ian P" sort="Hall, Ian P" uniqKey="Hall I" first="Ian P" last="Hall">Ian P. Hall</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21946350</idno><idno type="pmc">3267376</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267376</idno><idno type="RBID">PMC:3267376</idno><idno type="doi">10.1038/ng.941</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">002E07</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E07</idno><idno type="wicri:Area/Pmc/Curation">002C57</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C57</idno><idno type="wicri:Area/Pmc/Checkpoint">002304</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002304</idno><idno type="wicri:Area/Ncbi/Merge">000B78</idno><idno type="wicri:Area/Ncbi/Curation">000B78</idno><idno type="wicri:Area/Ncbi/Checkpoint">000B78</idno><idno type="wicri:doubleKey">1061-4036:2011:Artigas M:genome:wide:association</idno><idno type="wicri:Area/Main/Merge">006500</idno><idno type="wicri:Area/Main/Curation">006142</idno><idno type="wicri:Area/Main/Exploration">006142</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function</title><author><name sortKey="Artigas, Maria Soler" sort="Artigas, Maria Soler" uniqKey="Artigas M" first="María Soler" last="Artigas">María Soler Artigas</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Loth, Daan W" sort="Loth, Daan W" uniqKey="Loth D" first="Daan W" last="Loth">Daan W. Loth</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A4">Inspectorate of Healthcare, The Hague, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Inspectorate of Healthcare, The Hague</wicri:regionArea><wicri:noRegion>The Hague</wicri:noRegion></affiliation></author><author><name sortKey="Wain, Louise V" sort="Wain, Louise V" uniqKey="Wain L" first="Louise V" last="Wain">Louise V. Wain</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Gharib, Sina A" sort="Gharib, Sina A" uniqKey="Gharib S" first="Sina A" last="Gharib">Sina A. Gharib</name><affiliation wicri:level="4"><nlm:aff id="A5">Center for Lung Biology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Lung Biology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A6">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Obeidat, Ma N" sort="Obeidat, Ma N" uniqKey="Obeidat M" first="Ma N" last="Obeidat">Ma N Obeidat</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Tang, Wenbo" sort="Tang, Wenbo" uniqKey="Tang W" first="Wenbo" last="Tang">Wenbo Tang</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Nutritional Sciences, Cornell University Ithaca, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nutritional Sciences, Cornell University Ithaca, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Zhai, Guangju" sort="Zhai, Guangju" uniqKey="Zhai G" first="Guangju" last="Zhai">Guangju Zhai</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A10">Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland</wicri:regionArea><wicri:noRegion>Newfoundland</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:aff id="A11">Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E" last="Huffman">Jennifer E. Huffman</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation wicri:level="1"><nlm:aff id="A15">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Jackson, Catherine M" sort="Jackson, Catherine M" uniqKey="Jackson C" first="Catherine M" last="Jackson">Catherine M. Jackson</name><affiliation wicri:level="1"><nlm:aff id="A16">School of Medicine, University of St. Andrews, St. Andrews, Scotland, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Medicine, University of St. Andrews, St. Andrews, Scotland</wicri:regionArea><wicri:noRegion>Scotland</wicri:noRegion></affiliation></author><author><name sortKey="Evans, David M" sort="Evans, David M" uniqKey="Evans D" first="David M" last="Evans">David M. Evans</name><affiliation wicri:level="1"><nlm:aff id="A17">MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Cadby, Gemma" sort="Cadby, Gemma" uniqKey="Cadby G" first="Gemma" last="Cadby">Gemma Cadby</name><affiliation wicri:level="1"><nlm:aff id="A18">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><affiliation wicri:level="2"><nlm:aff id="A20">Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A21">Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Manichaikul, Ani" sort="Manichaikul, Ani" uniqKey="Manichaikul A" first="Ani" last="Manichaikul">Ani Manichaikul</name><affiliation wicri:level="2"><nlm:aff id="A22">Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A23">Department of Public Health Sciences, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, Virginia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, Virginia</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A25">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name><affiliation wicri:level="4"><nlm:aff id="A26">Clinical Pharmacology and the Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and the Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. Aldrich</name><affiliation wicri:level="2"><nlm:aff id="A27">Department of Thoracic Surgery, Vanderbilt University, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Thoracic Surgery, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A28">Division of Epidemiology, Vanderbilt University, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation wicri:level="1"><nlm:aff id="A29">Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A30">University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Cassano, Patricia A" sort="Cassano, Patricia A" uniqKey="Cassano P" first="Patricia A" last="Cassano">Patricia A. Cassano</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Nutritional Sciences, Cornell University Ithaca, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nutritional Sciences, Cornell University Ithaca, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Couper, David J" sort="Couper, David J" uniqKey="Couper D" first="David J" last="Couper">David J. Couper</name><affiliation wicri:level="2"><nlm:aff id="A32">Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Franceschini, Nora" sort="Franceschini, Nora" uniqKey="Franceschini N" first="Nora" last="Franceschini">Nora Franceschini</name><affiliation wicri:level="2"><nlm:aff id="A33">Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Garcia, Melissa" sort="Garcia, Melissa" uniqKey="Garcia M" first="Melissa" last="Garcia">Melissa Garcia</name><affiliation wicri:level="2"><nlm:aff id="A34">Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A15">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gislason, Gauti Kjartan" sort="Gislason, Gauti Kjartan" uniqKey="Gislason G" first="Gauti Kjartan" last="Gislason">Gauti Kjartan Gislason</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Grkovic, Ivica" sort="Grkovic, Ivica" uniqKey="Grkovic I" first="Ivica" last="Grkovic">Ivica Grkovic</name><affiliation wicri:level="1"><nlm:aff id="A35">Croatian Centre for Global Health, The University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, The University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Hammond, Christopher J" sort="Hammond, Christopher J" uniqKey="Hammond C" first="Christopher J" last="Hammond">Christopher J. Hammond</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hancock, Dana B" sort="Hancock, Dana B" uniqKey="Hancock D" first="Dana B" last="Hancock">Dana B. Hancock</name><affiliation wicri:level="2"><nlm:aff id="A36">Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A37">Behavioral Health Epidemiology Program, Research Triangle Institute International, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Behavioral Health Epidemiology Program, Research Triangle Institute International, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="2"><nlm:aff id="A34">Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><affiliation wicri:level="3"><nlm:aff id="A38"> Respiratory Epidemiology and Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Respiratory Epidemiology and Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A39">Department of Epidemiology and Biostatistics, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A40">Department of Medical and Molecular Genetics, King’s College London, Guy’s Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical and Molecular Genetics, King’s College London, Guy’s Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Heckbert, Susan R" sort="Heckbert, Susan R" uniqKey="Heckbert S" first="Susan R" last="Heckbert">Susan R. Heckbert</name><affiliation wicri:level="4"><nlm:aff id="A41">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A43">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><affiliation wicri:level="1"><nlm:aff id="A44">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation wicri:level="1"><nlm:aff id="A45">Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="James, Alan L" sort="James, Alan L" uniqKey="James A" first="Alan L" last="James">Alan L. James</name><affiliation wicri:level="1"><nlm:aff id="A46">Department of Pulmonary Physiology and Sleep Medicine/West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pulmonary Physiology and Sleep Medicine/West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A47">The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Jankovic, Stipan" sort="Jankovic, Stipan" uniqKey="Jankovic S" first="Stipan" last="Jankovic">Stipan Jankovic</name><affiliation wicri:level="1"><nlm:aff id="A35">Croatian Centre for Global Health, The University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, The University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Joubert, Bonnie R" sort="Joubert, Bonnie R" uniqKey="Joubert B" first="Bonnie R" last="Joubert">Bonnie R. Joubert</name><affiliation wicri:level="2"><nlm:aff id="A36">Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Karrasch, Stefan" sort="Karrasch, Stefan" uniqKey="Karrasch S" first="Stefan" last="Karrasch">Stefan Karrasch</name><affiliation wicri:level="4"><nlm:aff id="A49">Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name><affiliation wicri:level="1"><nlm:aff id="A50">Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Koch, Beate" sort="Koch, Beate" uniqKey="Koch B" first="Beate" last="Koch">Beate Koch</name><affiliation wicri:level="1"><nlm:aff id="A51">Department of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine B, University Hospital Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Kritchevsky, Stephen B" sort="Kritchevsky, Stephen B" uniqKey="Kritchevsky S" first="Stephen B" last="Kritchevsky">Stephen B. Kritchevsky</name><affiliation wicri:level="2"><nlm:aff id="A52">Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="2"><nlm:aff id="A34">Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation wicri:level="2"><nlm:aff id="A53">Epidemiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Loehr, Laura R" sort="Loehr, Laura R" uniqKey="Loehr L" first="Laura R" last="Loehr">Laura R. Loehr</name><affiliation wicri:level="2"><nlm:aff id="A33">Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Lohman, Kurt" sort="Lohman, Kurt" uniqKey="Lohman K" first="Kurt" last="Lohman">Kurt Lohman</name><affiliation wicri:level="2"><nlm:aff id="A54">Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Loos, Ruth Jf" sort="Loos, Ruth Jf" uniqKey="Loos R" first="Ruth Jf" last="Loos">Ruth Jf Loos</name><affiliation wicri:level="1"><nlm:aff id="A11">Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Lumley, Thomas" sort="Lumley, Thomas" uniqKey="Lumley T" first="Thomas" last="Lumley">Thomas Lumley</name><affiliation wicri:level="1"><nlm:aff id="A55">Department of Statistics, University of Auckland, Auckland, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Department of Statistics, University of Auckland, Auckland</wicri:regionArea><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Al Balushi, Khalid A" sort="Al Balushi, Khalid A" uniqKey="Al Balushi K" first="Khalid A" last="Al Balushi">Khalid A. Al Balushi</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ang, Wei Q" sort="Ang, Wei Q" uniqKey="Ang W" first="Wei Q" last="Ang">Wei Q. Ang</name><affiliation wicri:level="1"><nlm:aff id="A56">School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Barr, R Graham" sort="Barr, R Graham" uniqKey="Barr R" first="R Graham" last="Barr">R Graham Barr</name><affiliation wicri:level="2"><nlm:aff id="A57">Department of Medicine, Columbia University Medical Center, New York, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Columbia University Medical Center, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation wicri:level="1"><nlm:aff id="A58">Department of Surgery and Pathology, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Surgery and Pathology, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Blakey, John D" sort="Blakey, John D" uniqKey="Blakey J" first="John D" last="Blakey">John D. Blakey</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Boraska, Vesna" sort="Boraska, Vesna" uniqKey="Boraska V" first="Vesna" last="Boraska">Vesna Boraska</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Brisman, Jonas" sort="Brisman, Jonas" uniqKey="Brisman J" first="Jonas" last="Brisman">Jonas Brisman</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Britton, John R" sort="Britton, John R" uniqKey="Britton J" first="John R" last="Britton">John R. Britton</name><affiliation wicri:level="4"><nlm:aff id="A62">Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Brusselle, Guy G" sort="Brusselle, Guy G" uniqKey="Brusselle G" first="Guy G" last="Brusselle">Guy G. Brusselle</name><affiliation wicri:level="1"><nlm:aff id="A63">Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Respiratory Medicine, Ghent University Hospital, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name><affiliation wicri:level="1"><nlm:aff id="A64">MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Curjuric, Ivan" sort="Curjuric, Ivan" uniqKey="Curjuric I" first="Ivan" last="Curjuric">Ivan Curjuric</name><affiliation wicri:level="1"><nlm:aff id="A65">Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">University of Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Basel</wicri:regionArea></affiliation></author><author><name sortKey="Dahgam, Santosh" sort="Dahgam, Santosh" uniqKey="Dahgam S" first="Santosh" last="Dahgam">Santosh Dahgam</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A25">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Ebrahim, Shah" sort="Ebrahim, Shah" uniqKey="Ebrahim S" first="Shah" last="Ebrahim">Shah Ebrahim</name><affiliation wicri:level="3"><nlm:aff id="A67">Non-Communicable Diseases Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Non-Communicable Diseases Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A68">South Asia Centre for Chronic Disease, New Delhi, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>South Asia Centre for Chronic Disease, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Eijgelsheim, Mark" sort="Eijgelsheim, Mark" uniqKey="Eijgelsheim M" first="Mark" last="Eijgelsheim">Mark Eijgelsheim</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Francks, Clyde" sort="Francks, Clyde" uniqKey="Francks C" first="Clyde" last="Francks">Clyde Francks</name><affiliation wicri:level="3"><nlm:aff id="A69">Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Max Planck Institute for Psycholinguistics, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Gaysina, Darya" sort="Gaysina, Darya" uniqKey="Gaysina D" first="Darya" last="Gaysina">Darya Gaysina</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Granell, Raquel" sort="Granell, Raquel" uniqKey="Granell R" first="Raquel" last="Granell">Raquel Granell</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Gu, Xiangjun" sort="Gu, Xiangjun" uniqKey="Gu X" first="Xiangjun" last="Gu">Xiangjun Gu</name><affiliation wicri:level="2"><nlm:aff id="A20">Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brown Foundation Institute of Molecular Medicine, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Hankinson, John L" sort="Hankinson, John L" uniqKey="Hankinson J" first="John L" last="Hankinson">John L. Hankinson</name><affiliation wicri:level="2"><nlm:aff id="A72">Hankinson Consulting, Inc, Athens, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hankinson Consulting, Inc, Athens, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Hardy, Rebecca" sort="Hardy, Rebecca" uniqKey="Hardy R" first="Rebecca" last="Hardy">Rebecca Hardy</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Harris, Sarah E" sort="Harris, Sarah E" uniqKey="Harris S" first="Sarah E" last="Harris">Sarah E. Harris</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A73">Medical Genetics Section, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Section, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Henderson, John" sort="Henderson, John" uniqKey="Henderson J" first="John" last="Henderson">John Henderson</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Henry, Amanda" sort="Henry, Amanda" uniqKey="Henry A" first="Amanda" last="Henry">Amanda Henry</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hingorani, Aroon D" sort="Hingorani, Aroon D" uniqKey="Hingorani A" first="Aroon D" last="Hingorani">Aroon D. Hingorani</name><affiliation wicri:level="4"><nlm:aff id="A74">Department of Epidemiology and Public Health, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation></author><author><name sortKey="Holt, Patrick G" sort="Holt, Patrick G" uniqKey="Holt P" first="Patrick G" last="Holt">Patrick G. Holt</name><affiliation wicri:level="1"><nlm:aff id="A76">Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A77">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A78">School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Hunter, Michael L" sort="Hunter, Michael L" uniqKey="Hunter M" first="Michael L" last="Hunter">Michael L. Hunter</name><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A78">School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Imboden, Medea" sort="Imboden, Medea" uniqKey="Imboden M" first="Medea" last="Imboden">Medea Imboden</name><affiliation wicri:level="1"><nlm:aff id="A65">Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">University of Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Basel</wicri:regionArea></affiliation></author><author><name sortKey="Jameson, Karen A" sort="Jameson, Karen A" uniqKey="Jameson K" first="Karen A" last="Jameson">Karen A. Jameson</name><affiliation wicri:level="1"><nlm:aff id="A64">MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Kerr, Shona M" sort="Kerr, Shona M" uniqKey="Kerr S" first="Shona M" last="Kerr">Shona M. Kerr</name><affiliation wicri:level="4"><nlm:aff id="A79">Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Kronenberg, Florian" sort="Kronenberg, Florian" uniqKey="Kronenberg F" first="Florian" last="Kronenberg">Florian Kronenberg</name><affiliation wicri:level="1"><nlm:aff id="A80">Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Jason Z" sort="Liu, Jason Z" uniqKey="Liu J" first="Jason Z" last="Liu">Jason Z. Liu</name><affiliation wicri:level="4"><nlm:aff id="A81">Department of Statistics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Statistics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Marchini, Jonathan" sort="Marchini, Jonathan" uniqKey="Marchini J" first="Jonathan" last="Marchini">Jonathan Marchini</name><affiliation wicri:level="4"><nlm:aff id="A81">Department of Statistics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Statistics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Mckeever, Tricia" sort="Mckeever, Tricia" uniqKey="Mckeever T" first="Tricia" last="Mckeever">Tricia Mckeever</name><affiliation wicri:level="4"><nlm:aff id="A62">Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Epidemiology and Public Health, School of Community Health Sciences and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><affiliation wicri:level="1"><nlm:aff id="A82">Medical Research Institute, The University of Dundee, Dundee, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Institute, The University of Dundee, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Olin, Anna Carin" sort="Olin, Anna Carin" uniqKey="Olin A" first="Anna-Carin" last="Olin">Anna-Carin Olin</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Porteous, David J" sort="Porteous, David J" uniqKey="Porteous D" first="David J" last="Porteous">David J. Porteous</name><affiliation wicri:level="4"><nlm:aff id="A79">Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S" last="Postma">Dirkje S. Postma</name><affiliation wicri:level="3"><nlm:aff id="A83">Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Rich, Stephen S" sort="Rich, Stephen S" uniqKey="Rich S" first="Stephen S" last="Rich">Stephen S. Rich</name><affiliation wicri:level="2"><nlm:aff id="A22">Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Ring, Susan M" sort="Ring, Susan M" uniqKey="Ring S" first="Susan M" last="Ring">Susan M. Ring</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation></author><author><name sortKey="Rochat, Thierry" sort="Rochat, Thierry" uniqKey="Rochat T" first="Thierry" last="Rochat">Thierry Rochat</name><affiliation wicri:level="1"><nlm:aff id="A85">Division of Pulmonary Medicine, University Hospitals of Geneva, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Division of Pulmonary Medicine, University Hospitals of Geneva, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Sayer, Avan Aihie" sort="Sayer, Avan Aihie" uniqKey="Sayer A" first="Avan Aihie" last="Sayer">Avan Aihie Sayer</name><affiliation wicri:level="1"><nlm:aff id="A64">MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Sayers, Ian" sort="Sayers, Ian" uniqKey="Sayers I" first="Ian" last="Sayers">Ian Sayers</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sly, Peter D" sort="Sly, Peter D" uniqKey="Sly P" first="Peter D" last="Sly">Peter D. Sly</name><affiliation wicri:level="1"><nlm:aff id="A76">Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Telethon Institute for Child Health Research and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name><affiliation wicri:level="1"><nlm:aff id="A17">MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Sood, Akshay" sort="Sood, Akshay" uniqKey="Sood A" first="Akshay" last="Sood">Akshay Sood</name><affiliation wicri:level="2"><nlm:aff id="A86">Department of Medicine, University of New Mexico, Albuquerque, New Mexico, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of New Mexico, Albuquerque, New Mexico</wicri:regionArea><placeName><region type="state">Nouveau-Mexique</region></placeName></affiliation></author><author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><affiliation wicri:level="4"><nlm:aff id="A24">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A87">Geriatric Medicine Unit, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Geriatric Medicine Unit, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation></author><author><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M" last="Vonk">Judith M. Vonk</name><affiliation wicri:level="3"><nlm:aff id="A88">Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Wannamethee, S Goya" sort="Wannamethee, S Goya" uniqKey="Wannamethee S" first="S Goya" last="Wannamethee">S Goya Wannamethee</name><affiliation wicri:level="4"><nlm:aff id="A89">Department of Primary Care and Population Health, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Primary Care and Population Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Whincup, Peter H" sort="Whincup, Peter H" uniqKey="Whincup P" first="Peter H" last="Whincup">Peter H. Whincup</name><affiliation wicri:level="4"><nlm:aff id="A90">Division of Population Health Sciences and Education, St George’s University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health Sciences and Education, St George’s University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Wijmenga, Cisca" sort="Wijmenga, Cisca" uniqKey="Wijmenga C" first="Cisca" last="Wijmenga">Cisca Wijmenga</name><affiliation wicri:level="3"><nlm:aff id="A91">Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Williams, O Dale" sort="Williams, O Dale" uniqKey="Williams O" first="O Dale" last="Williams">O Dale Williams</name><affiliation wicri:level="3"><nlm:aff id="A92">Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Marciante, Kristin D" sort="Marciante, Kristin D" uniqKey="Marciante K" first="Kristin D" last="Marciante">Kristin D. Marciante</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A41">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><affiliation wicri:level="1"><nlm:aff id="A71">School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Meibohm, Bernd" sort="Meibohm, Bernd" uniqKey="Meibohm B" first="Bernd" last="Meibohm">Bernd Meibohm</name><affiliation wicri:level="2"><nlm:aff id="A93">College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><affiliation wicri:level="2"><nlm:aff id="A21">Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, University of Texas at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><affiliation wicri:level="2"><nlm:aff id="A33">Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Omenaas, Ernst" sort="Omenaas, Ernst" uniqKey="Omenaas E" first="Ernst" last="Omenaas">Ernst Omenaas</name><affiliation wicri:level="1"><nlm:aff id="A94">Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Centre for Clinical Research, Haukeland University Hospital, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><affiliation wicri:level="1"><nlm:aff id="A18">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H" last="Pietil Inen">Kirsi H. Pietil Inen</name><affiliation wicri:level="1"><nlm:aff id="A95">Obesity Research Unit, Department of Medicine, Division of Internal Medicine, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Obesity Research Unit, Department of Medicine, Division of Internal Medicine, Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A96">Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Pin, Isabelle" sort="Pin, Isabelle" uniqKey="Pin I" first="Isabelle" last="Pin">Isabelle Pin</name><affiliation wicri:level="3"><nlm:aff id="A98">Pédiatrie, Centre Hospitalier Universitaire (CHU), Grenoble, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Pédiatrie, Centre Hospitalier Universitaire (CHU), Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A99">Inserm U823, Centre de Recherche Albert Bonniot, Grenoble, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm U823, Centre de Recherche Albert Bonniot, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A100">Université Joseph Fourier, Grenoble, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Joseph Fourier, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Joseph Fourier</orgName></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A101">Gen-Info Ltd, Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Gen-Info Ltd, Zagreb</wicri:regionArea><wicri:noRegion>Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><affiliation wicri:level="1"><nlm:aff id="A102">Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A41">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A43">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Hartikainen, Anna Liisa" sort="Hartikainen, Anna Liisa" uniqKey="Hartikainen A" first="Anna-Liisa" last="Hartikainen">Anna-Liisa Hartikainen</name><affiliation wicri:level="1"><nlm:aff id="A103">Institute of Clinical Medicine, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Clinical Medicine, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Rantanen, Taina" sort="Rantanen, Taina" uniqKey="Rantanen T" first="Taina" last="Rantanen">Taina Rantanen</name><affiliation wicri:level="4"><nlm:aff id="A104"> Gerontology Research Centre, Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea> Gerontology Research Centre, Department of Health Sciences, University of Jyväskylä, Jyväskylä</wicri:regionArea><orgName type="university">Université de Jyväskylä</orgName><placeName><settlement type="city">Jyväskylä</settlement><region type="région" nuts="2">Finlande-Centrale</region></placeName></affiliation></author><author><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A105">Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="2"><nlm:aff id="A106">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A35">Croatian Centre for Global Health, The University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, The University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A101">Gen-Info Ltd, Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Gen-Info Ltd, Zagreb</wicri:regionArea><wicri:noRegion>Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Rudnicka, Alicja R" sort="Rudnicka, Alicja R" uniqKey="Rudnicka A" first="Alicja R" last="Rudnicka">Alicja R. Rudnicka</name><affiliation wicri:level="4"><nlm:aff id="A90">Division of Population Health Sciences and Education, St George’s University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health Sciences and Education, St George’s University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Schulz, Holger" sort="Schulz, Holger" uniqKey="Schulz H" first="Holger" last="Schulz">Holger Schulz</name><affiliation wicri:level="1"><nlm:aff id="A107">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><affiliation wicri:level="1"><nlm:aff id="A29">Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="3"><nlm:aff id="A9">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Surakka, Ida" sort="Surakka, Ida" uniqKey="Surakka I" first="Ida" last="Surakka">Ida Surakka</name><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A105">Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Public Health Genomics Unit, Department Of Chronic Disease Prevention, The National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:aff id="A108">Institute for Community Medicine, Study of Health In Pomerania (SHIP)/Clinical Epidemiological Research, University of Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, Study of Health In Pomerania (SHIP)/Clinical Epidemiological Research, University of Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A11">Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Warrington, Nicole M" sort="Warrington, Nicole M" uniqKey="Warrington N" first="Nicole M" last="Warrington">Nicole M. Warrington</name><affiliation wicri:level="1"><nlm:aff id="A56">School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation wicri:level="1"><nlm:aff id="A107">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A109">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A110">Klinikum Grosshadern, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinikum Grosshadern, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Wilk, Jemma B" sort="Wilk, Jemma B" uniqKey="Wilk J" first="Jemma B" last="Wilk">Jemma B. Wilk</name><affiliation wicri:level="2"><nlm:aff id="A111">Division of Aging, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Aging, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Wjst, Matthias" sort="Wjst, Matthias" uniqKey="Wjst M" first="Matthias" last="Wjst">Matthias Wjst</name><affiliation wicri:level="1"><nlm:aff id="A112">Institute of Lung Biology and Disease, Comprehensive Pneumology Center, Helmholtz Zentrum München, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Lung Biology and Disease, Comprehensive Pneumology Center, Helmholtz Zentrum München, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A113">Institute for Medical Statistics and Epidemiology (IMSE), Technical University Munich, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Statistics and Epidemiology (IMSE), Technical University Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Zgaga, Lina" sort="Zgaga, Lina" uniqKey="Zgaga L" first="Lina" last="Zgaga">Lina Zgaga</name><affiliation wicri:level="1"><nlm:aff id="A114">Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb</wicri:regionArea><wicri:noRegion>Zagreb</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name><affiliation wicri:level="1"><nlm:aff id="A60">Faculty of Medicine, University of Split, Croatia, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Croatia, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E" last="Pennell">Craig E. Pennell</name><affiliation wicri:level="1"><nlm:aff id="A56">School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Women’s and Infants’ Health, The University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Nyberg, Fredrik" sort="Nyberg, Fredrik" uniqKey="Nyberg F" first="Fredrik" last="Nyberg">Fredrik Nyberg</name><affiliation wicri:level="1"><nlm:aff id="A61">Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A115">AstraZeneca Research and Development, Mölndal, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>AstraZeneca Research and Development, Mölndal</wicri:regionArea><wicri:noRegion>Mölndal</wicri:noRegion></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation wicri:level="3"><nlm:aff id="A70">MRC Unit for Lifelong Health and Ageing, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health and Ageing, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Holloway, John W" sort="Holloway, John W" uniqKey="Holloway J" first="John W" last="Holloway">John W. Holloway</name><affiliation wicri:level="1"><nlm:aff id="A116">Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Human Development and Health, Faculty of Medicine, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A117">Infection, Inflammation and Immunity, Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Infection, Inflammation and Immunity, Faculty of Medicine, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Boezen, H Marike" sort="Boezen, H Marike" uniqKey="Boezen H" first="H Marike" last="Boezen">H Marike Boezen</name><affiliation wicri:level="3"><nlm:aff id="A88">Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Lawlor, Debbie A" sort="Lawlor, Debbie A" uniqKey="Lawlor D" first="Debbie A" last="Lawlor">Debbie A. Lawlor</name><affiliation wicri:level="1"><nlm:aff id="A17">MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Richard W" sort="Morris, Richard W" uniqKey="Morris R" first="Richard W" last="Morris">Richard W. Morris</name><affiliation wicri:level="4"><nlm:aff id="A89">Department of Primary Care and Population Health, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Primary Care and Population Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Probst Hensch, Nicole" sort="Probst Hensch, Nicole" uniqKey="Probst Hensch N" first="Nicole" last="Probst-Hensch">Nicole Probst-Hensch</name><affiliation wicri:level="1"><nlm:aff id="A65">Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Chronic Disease Epidemiology, Swiss Tropical and Public Health (TPH) Institute, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">University of Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Basel</wicri:regionArea></affiliation></author><author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name><affiliation wicri:level="1"><nlm:aff id="A44">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A96">Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A97">Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A31">Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="3"><nlm:aff id="A14">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:aff id="A118">Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Heinrich, Joachim" sort="Heinrich, Joachim" uniqKey="Heinrich J" first="Joachim" last="Heinrich">Joachim Heinrich</name><affiliation wicri:level="1"><nlm:aff id="A107">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Musk, Arthur W" sort="Musk, Arthur W" uniqKey="Musk A" first="Arthur W" last="Musk">Arthur W. Musk</name><affiliation wicri:level="1"><nlm:aff id="A48">Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A119">Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A78">School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A47">The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>The School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Jarvis, Deborah L" sort="Jarvis, Deborah L" uniqKey="Jarvis D" first="Deborah L" last="Jarvis">Deborah L. Jarvis</name><affiliation wicri:level="3"><nlm:aff id="A38"> Respiratory Epidemiology and Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Respiratory Epidemiology and Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A120">MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Gl Ser, Sven" sort="Gl Ser, Sven" uniqKey="Gl Ser S" first="Sven" last="Gl Ser">Sven Gl Ser</name><affiliation wicri:level="1"><nlm:aff id="A121">University Hospital Greifswald, Department of Internal Medicine B, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Greifswald, Department of Internal Medicine B, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><affiliation wicri:level="3"><nlm:aff id="A39">Department of Epidemiology and Biostatistics, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A122">Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A123">Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A102">Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A120">MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A4">Inspectorate of Healthcare, The Hague, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Inspectorate of Healthcare, The Hague</wicri:regionArea><wicri:noRegion>The Hague</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</wicri:regionArea></affiliation><affiliation wicri:level="3"><nlm:aff id="A124">Department of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Informatics, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><affiliation wicri:level="3"><nlm:aff id="A120">MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A39">Department of Epidemiology and Biostatistics, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="O Onnor, George T" sort="O Onnor, George T" uniqKey="O Onnor G" first="George T" last="O Onnor">George T. O Onnor</name><affiliation wicri:level="2"><nlm:aff id="A125">Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A126">The National Heart, Lung and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The National Heart, Lung and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><affiliation wicri:level="4"><nlm:aff id="A90">Division of Population Health Sciences and Education, St George’s University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health Sciences and Education, St George’s University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="London, Stephanie J" sort="London, Stephanie J" uniqKey="London S" first="Stephanie J" last="London">Stephanie J. London</name><affiliation wicri:level="2"><nlm:aff id="A36">Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Hall, Ian P" sort="Hall, Ian P" uniqKey="Hall I" first="Ian P" last="Hall">Ian P. Hall</name><affiliation wicri:level="3"><nlm:aff id="A7">Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Therapeutics and Molecular Medicine, Nottingham Respiratory Biomedical Research Unit, University Hospital of Nottingham, Nottingham, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A12">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P3">Pulmonary function measures reflect respiratory health and predict mortality, and are used in the diagnosis of chronic obstructive pulmonary disease (COPD). We tested genome-wide association with the forced expiratory volume in 1 second (FEV<sub>1</sub>) and the ratio of FEV<sub>1</sub> to forced vital capacity (FVC) in 48,201 individuals of European ancestry, with follow-up of top associations in up to an additional 46,411 individuals. We identified new regions showing association (combined <italic>P</italic><5×10<sup>−8</sup>) with pulmonary function, in or near <italic>MFAP2, TGFB2, HDAC4, RARB, MECOM</italic> (<italic>EVI1</italic>), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1, and <italic>KCNE2</italic>. Identification of these 16 new loci may provide insight into the molecular mechanisms regulating pulmonary function and into molecular targets for future therapy to alleviate reduced lung function.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wilk, Jb" uniqKey="Wilk J">JB Wilk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hole, Dj" uniqKey="Hole D">DJ Hole</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Strachan, Dp" uniqKey="Strachan D">DP Strachan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Young, Rp" uniqKey="Young R">RP Young</name></author><author><name sortKey="Hopkins, R" uniqKey="Hopkins R">R Hopkins</name></author><author><name sortKey="Eaton, Te" uniqKey="Eaton T">TE Eaton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lopez, Ad" uniqKey="Lopez A">AD 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Stetefeld</name></author><author><name sortKey="Strelkov, Sv" uniqKey="Strelkov S">SV Strelkov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cowley, Ea" uniqKey="Cowley E">EA Cowley</name></author><author><name sortKey="Linsdell, P" uniqKey="Linsdell P">P Linsdell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author><author><name sortKey="Abecasis, Gr" uniqKey="Abecasis G">GR Abecasis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marchini, J" uniqKey="Marchini J">J Marchini</name></author><author><name sortKey="Howie, B" uniqKey="Howie B">B Howie</name></author><author><name sortKey="Myers, S" uniqKey="Myers S">S Myers</name></author><author><name sortKey="Mcvean, G" uniqKey="Mcvean G">G McVean</name></author><author><name sortKey="Donnelly, P" uniqKey="Donnelly P">P Donnelly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Servin, B" uniqKey="Servin B">B Servin</name></author><author><name sortKey="Stephens, M" uniqKey="Stephens M">M Stephens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Devlin, B" uniqKey="Devlin B">B Devlin</name></author><author><name sortKey="Roeder, K" uniqKey="Roeder K">K Roeder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, Mh" uniqKey="Cho M">MH Cho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pillai, Sg" uniqKey="Pillai S">SG Pillai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Segre, Av" uniqKey="Segre A">AV Segre</name></author><author><name sortKey="Groop, L" uniqKey="Groop L">L Groop</name></author><author><name sortKey="Mootha, Vk" uniqKey="Mootha V">VK Mootha</name></author><author><name sortKey="Daly, Mj" uniqKey="Daly M">MJ Daly</name></author><author><name sortKey="Altshuler, D" uniqKey="Altshuler D">D Altshuler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raychaudhuri, S" uniqKey="Raychaudhuri S">S Raychaudhuri</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Croatie</li><li>Finlande</li><li>France</li><li>Inde</li><li>Islande</li><li>Norvège</li><li>Nouvelle-Zélande</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Auvergne-Rhône-Alpes</li><li>Bavière</li><li>Californie</li><li>Caroline du Nord</li><li>District de Haute-Bavière</li><li>Finlande-Centrale</li><li>Grand Londres</li><li>Groningue (province)</li><li>Gueldre</li><li>Géorgie (États-Unis)</li><li>Hollande-Méridionale</li><li>Maryland</li><li>Massachusetts</li><li>Midlands de l'Ouest</li><li>Nottinghamshire</li><li>Nouveau-Mexique</li><li>Oxfordshire</li><li>Rhône-Alpes</li><li>Tennessee</li><li>Texas</li><li>Uusimaa</li><li>Virginie</li><li>Washington (État)</li><li>Écosse</li><li>État de New York</li></region><settlement><li>Birmingham</li><li>Grenoble</li><li>Groningue</li><li>Helsinki</li><li>Jyväskylä</li><li>Londres</li><li>Munich</li><li>Nimègue</li><li>Nottingham</li><li>Oxford</li><li>Rotterdam</li><li>Seattle</li><li>Édimbourg</li></settlement><orgName><li>University College de Londres</li><li>Université Joseph Fourier</li><li>Université Louis-et-Maximilien de Munich</li><li>Université d'Helsinki</li><li>Université d'Oxford</li><li>Université d'Édimbourg</li><li>Université de Jyväskylä</li><li>Université de Londres</li><li>Université de Nottingham</li><li>Université de Washington</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Artigas, Maria Soler" sort="Artigas, Maria Soler" uniqKey="Artigas M" first="María Soler" last="Artigas">María Soler Artigas</name></noRegion><name sortKey="Al Balushi, Khalid A" sort="Al Balushi, Khalid A" uniqKey="Al Balushi K" first="Khalid A" last="Al Balushi">Khalid A. Al Balushi</name><name sortKey="Artigas, Maria Soler" sort="Artigas, Maria Soler" uniqKey="Artigas M" first="María Soler" last="Artigas">María Soler Artigas</name><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><name sortKey="Blakey, John D" sort="Blakey, John D" uniqKey="Blakey J" first="John D" last="Blakey">John D. Blakey</name><name sortKey="Britton, John R" sort="Britton, John R" uniqKey="Britton J" first="John R" last="Britton">John R. Britton</name><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><name sortKey="Ebrahim, Shah" sort="Ebrahim, Shah" uniqKey="Ebrahim S" first="Shah" last="Ebrahim">Shah Ebrahim</name><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><name sortKey="Evans, David M" sort="Evans, David M" uniqKey="Evans D" first="David M" last="Evans">David M. Evans</name><name sortKey="Gaysina, Darya" sort="Gaysina, Darya" uniqKey="Gaysina D" first="Darya" last="Gaysina">Darya Gaysina</name><name sortKey="Granell, Raquel" sort="Granell, Raquel" uniqKey="Granell R" first="Raquel" last="Granell">Raquel Granell</name><name sortKey="Hall, Ian P" sort="Hall, Ian P" uniqKey="Hall I" first="Ian P" last="Hall">Ian P. Hall</name><name sortKey="Hammond, Christopher J" sort="Hammond, Christopher J" uniqKey="Hammond C" first="Christopher J" last="Hammond">Christopher J. Hammond</name><name sortKey="Hardy, Rebecca" sort="Hardy, Rebecca" uniqKey="Hardy R" first="Rebecca" last="Hardy">Rebecca Hardy</name><name sortKey="Harris, Sarah E" sort="Harris, Sarah E" uniqKey="Harris S" first="Sarah E" last="Harris">Sarah E. Harris</name><name sortKey="Harris, Sarah E" sort="Harris, Sarah E" uniqKey="Harris S" first="Sarah E" last="Harris">Sarah E. Harris</name><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><name sortKey="Henderson, John" sort="Henderson, John" uniqKey="Henderson J" first="John" last="Henderson">John Henderson</name><name sortKey="Henry, Amanda" sort="Henry, Amanda" uniqKey="Henry A" first="Amanda" last="Henry">Amanda Henry</name><name sortKey="Hingorani, Aroon D" sort="Hingorani, Aroon D" uniqKey="Hingorani A" first="Aroon D" last="Hingorani">Aroon D. Hingorani</name><name sortKey="Holloway, John W" sort="Holloway, John W" uniqKey="Holloway J" first="John W" last="Holloway">John W. Holloway</name><name sortKey="Holloway, John W" sort="Holloway, John W" uniqKey="Holloway J" first="John W" last="Holloway">John W. Holloway</name><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E" last="Huffman">Jennifer E. Huffman</name><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><name sortKey="Jackson, Catherine M" sort="Jackson, Catherine M" uniqKey="Jackson C" first="Catherine M" last="Jackson">Catherine M. Jackson</name><name sortKey="Jameson, Karen A" sort="Jameson, Karen A" uniqKey="Jameson K" first="Karen A" last="Jameson">Karen A. Jameson</name><name sortKey="Jarvis, Deborah L" sort="Jarvis, Deborah L" uniqKey="Jarvis D" first="Deborah L" last="Jarvis">Deborah L. Jarvis</name><name sortKey="Jarvis, Deborah L" sort="Jarvis, Deborah L" uniqKey="Jarvis D" first="Deborah L" last="Jarvis">Deborah L. Jarvis</name><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name><name sortKey="Kerr, Shona M" sort="Kerr, Shona M" uniqKey="Kerr S" first="Shona M" last="Kerr">Shona M. Kerr</name><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><name sortKey="Lawlor, Debbie A" sort="Lawlor, Debbie A" uniqKey="Lawlor D" first="Debbie A" last="Lawlor">Debbie A. Lawlor</name><name sortKey="Liu, Jason Z" sort="Liu, Jason Z" uniqKey="Liu J" first="Jason Z" last="Liu">Jason Z. Liu</name><name sortKey="Loos, Ruth Jf" sort="Loos, Ruth Jf" uniqKey="Loos R" first="Ruth Jf" last="Loos">Ruth Jf Loos</name><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><name sortKey="Marchini, Jonathan" sort="Marchini, Jonathan" uniqKey="Marchini J" first="Jonathan" last="Marchini">Jonathan Marchini</name><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><name sortKey="Mckeever, Tricia" sort="Mckeever, Tricia" uniqKey="Mckeever T" first="Tricia" last="Mckeever">Tricia Mckeever</name><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><name sortKey="Morris, Richard W" sort="Morris, Richard W" uniqKey="Morris R" first="Richard W" last="Morris">Richard W. Morris</name><name sortKey="Obeidat, Ma N" sort="Obeidat, Ma N" uniqKey="Obeidat M" first="Ma N" last="Obeidat">Ma N Obeidat</name><name sortKey="Porteous, David J" sort="Porteous, David J" uniqKey="Porteous D" first="David J" last="Porteous">David J. Porteous</name><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><name sortKey="Ring, Susan M" sort="Ring, Susan M" uniqKey="Ring S" first="Susan M" last="Ring">Susan M. Ring</name><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><name sortKey="Rudnicka, Alicja R" sort="Rudnicka, Alicja R" uniqKey="Rudnicka A" first="Alicja R" last="Rudnicka">Alicja R. Rudnicka</name><name sortKey="Sayer, Avan Aihie" sort="Sayer, Avan Aihie" uniqKey="Sayer A" first="Avan Aihie" last="Sayer">Avan Aihie Sayer</name><name sortKey="Sayers, Ian" sort="Sayers, Ian" uniqKey="Sayers I" first="Ian" last="Sayers">Ian Sayers</name><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><name sortKey="Wain, Louise V" sort="Wain, Louise V" uniqKey="Wain L" first="Louise V" last="Wain">Louise V. Wain</name><name sortKey="Wain, Louise V" sort="Wain, Louise V" uniqKey="Wain L" first="Louise V" last="Wain">Louise V. Wain</name><name sortKey="Wannamethee, S Goya" sort="Wannamethee, S Goya" uniqKey="Wannamethee S" first="S Goya" last="Wannamethee">S Goya Wannamethee</name><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><name sortKey="Whincup, Peter H" sort="Whincup, Peter H" uniqKey="Whincup P" first="Peter H" last="Whincup">Peter H. Whincup</name><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><name sortKey="Zgaga, Lina" sort="Zgaga, Lina" uniqKey="Zgaga L" first="Lina" last="Zgaga">Lina Zgaga</name><name sortKey="Zhai, Guangju" sort="Zhai, Guangju" uniqKey="Zhai G" first="Guangju" last="Zhai">Guangju Zhai</name><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Loth, Daan W" sort="Loth, Daan W" uniqKey="Loth D" first="Daan W" last="Loth">Daan W. Loth</name></region><name sortKey="Boezen, H Marike" sort="Boezen, H Marike" uniqKey="Boezen H" first="H Marike" last="Boezen">H Marike Boezen</name><name sortKey="Eijgelsheim, Mark" sort="Eijgelsheim, Mark" uniqKey="Eijgelsheim M" first="Mark" last="Eijgelsheim">Mark Eijgelsheim</name><name sortKey="Francks, Clyde" sort="Francks, Clyde" uniqKey="Francks C" first="Clyde" last="Francks">Clyde Francks</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Loth, Daan W" sort="Loth, Daan W" uniqKey="Loth D" first="Daan W" last="Loth">Daan W. Loth</name><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S" last="Postma">Dirkje S. Postma</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><name sortKey="Stricker, Bruno H Ch" sort="Stricker, Bruno H Ch" uniqKey="Stricker B" first="Bruno H Ch" last="Stricker">Bruno H Ch Stricker</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M" last="Vonk">Judith M. Vonk</name><name sortKey="Wijmenga, Cisca" sort="Wijmenga, Cisca" uniqKey="Wijmenga C" first="Cisca" last="Wijmenga">Cisca Wijmenga</name></country><country name="États-Unis"><region name="Washington (État)"><name sortKey="Gharib, Sina A" sort="Gharib, Sina A" uniqKey="Gharib S" first="Sina A" last="Gharib">Sina A. Gharib</name></region><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. 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|type= RBID
|clé= PMC:3267376
|texte= Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function
}}
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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21946350" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
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